https://gydb.org/index.php?action=history&feed=atom&title=Element%3AAmn-sanElement:Amn-san - Revision history2026-06-09T16:15:02ZRevision history for this page on the wikiMediaWiki 1.35.0https://gydb.org/index.php?title=Element:Amn-san&diff=578&oldid=previmported>Gydbwiki at 19:13, 15 June 20202020-06-15T19:13:58Z<p></p>
<p><b>New page</b></p><div>{{Element<br />
|genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=111608668 111608668]<br />
|type= <br />
V-clade<br />
|genus=<br />
Fungi and vertebrates<br />
|subfamily=<br />
Chromoviruses<br />
|family=<br />
Ty3/Gypsy<br />
|group=<br />
LTR retroelements<br />
|description=<br />
''Amn-san'' is a LTR retrotransposon characterized in the ''Xenopus (Silurana) tropicalis''. This element belongs to V-clade ([[Literature:100596|Llorens et al. 2009]]) the chromovirus lineage of vertebrate-like ''Ty3/Gypsy'' LTR retrotransposons ([[Literature:47259|Mar&iacute;n and Llor&eacute;ns 2000]]) characterized by encoding for chromodomain-integrases ([[Literature:46552|Malik and Eickbush 1999]]). The chromovirus branch has been disclosed to be the most ancient phylogenetic pattern of ''Ty3/Gypsy'' retroelements ([[Literature:26737|Gorinsek, Gubensek and Kordis 2004]]; [[Literature:26736| 2005]]; [[Literature:39523|Kordis 2005]]).<br />
<br />
The genomic structure of ''Amn-san'' is 4.9 Kb in size, including LTRs of 236-239 nt. The internal region of this element displays a Primer Binding site (PBS), two Open Reading Frames (ORFs) for gag, and pol genes, and a Polypurine Tract (PPT) adjacent to the 3´LTR ([[Literature:100596|Llorens et al. 2009]]). This element presents a detectable chromodomain at the C-terminal end of integrase. The PBS of fungi and vertebrate chromoviruses, differs significantly from that used by plant chromoviruses. While plant chromoviruses use a methionine starting tRNA (iMet), fungi and vertebrate chromoviruses use their own self-priming mechanism to start the reverse transcription ([[Literature:43217|Levin 1995 ]]; [[Literature:10125|Butler et al. 2001]]). <br />
|structure=<br />
amn-san.png<br />
|host= Xenopus (Silurana) tropicalis<br />
|hostpic=xenopus_tropicalis.jpg<br />
|literature=*[[Literature:15303|Mobile DNA II. (Craig et al. 2002)]]<br />
|picowner=[http://www.dbsm.uninsubria.it/biocel/images/tropicalis.JPG Courtesy of Dep. Biotechnology & Molecular Sciences (DBSM) of "University of Insubria", Italy]<br />
}}<br />
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