imported>Gydbwiki at 16:28, 11 November 2009

2009-11-11T16:28:01Z

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{{Element
|genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=2562 Z11866]
|type=Pyret
|genus=Fungi and vertebrates
|subfamily=Chromoviruses
|family=Ty3/Gypsy
|group=LTR Retroelements
|description=''Cft-1'' is a LTR retrotransposon characterized in the genome of ''Cladosporium fulvum'' ([[Literature:49102|McHale et al. 1992]]). This element belongs to the ''Chromoviridae'' branch, term suggested ([[Literature:47259|Marín and Lloréns 2000]]) to describe the ''Ty3/Gypsy'' elements bearing chromodomain-integrases ([[Literature:46552|Malik and Eickbush 1999]]). The chromovirus branch is probably the most ancient phylogenetic pattern of ''Ty3/Gypsy'' retroelements ([[Literature:26737|Gorinsek, Gubensek and Kordis 2004]]; [[Literature:26736| 2005]]; [[Literature:39523|Kordis 2005]]).

The genomic structure of ''Cft-1'' is 7.4 Kb in size, including LTRs of 427 nt. The internal region of this element displays a Primer Binding site (PBS), two ORFs for ''gag'', and ''pol'' genes, and a Polypurine Tract (PPT) adjacent to the 3´LTR ([[Literature:49102|McHale et al. 1992]]). This element presents a detectable chromodomain at the C-terminal end of the integrase. The PBS of fungi and vertebrate chromoviruses, differs significantly from that used by plant chromoviruses. While plant chromoviruses use a methionine starting tRNA (iMet), fungi and vertebrate chromoviruses use their own self-priming mechanism to start the reverse transcription ([[Literature:43217|Levin 1995 ]]; [[Literature:10125|Butler et al. 2001]]).
|structure=Cft-1.png
|host=Cladosporium fulvum
|hostpic=Cladosporium_fulvum.gif
|literature=*[[Literature:15303|Mobile DNA II. (Craig et al. 2002)]]
|picowner=[http://(www.php.wur.nl/uk Image,courtesy of Pierre J.G.M. de Wit, Wageningen University]
}}

Element:Cft-1 - Revision history

imported>Gydbwiki at 16:28, 11 November 2009