imported>Gydbwiki at 16:26, 11 November 2009

2009-11-11T16:26:07Z

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{{Element
|genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=11559706 AF295689]
|type=
Maggy
|genus=
Fungi and vertebrates
|subfamily=
Chromoviruses
|family=
Ty3/Gypsy
|group=
LTR retroelements
|description=''Dane-1'' is a LTR retrotransposon characterized in ''Aspergillus nidulans'' ([[Literature:85408|Nielsen, Hermansen and Aleksenko 2000]]). ''Dane-1'' belongs to the ''Chromoviridae ''branch, term suggested ([[Literature:47259|Marín and Lloréns 2000]]) to describe the ''Ty3/Gypsy'' elements bearing chromodomain-integrases ([[Literature:46552|Malik and Eickbush 1999]]). The chromovirus branch is probably the most ancient phylogenetic pattern of ''Ty3/Gypsy'' retroelements ([[Literature:26737|Gorinsek, Gubensek and Kordis 2004]]; [[Literature:26736| 2005]]; [[Literature:39523|Kordis 2005]]).

The genomic structure of ''Dane-1'' is 7.7 Kb in size, including LTRs of 223 nt. The internal region of this element displays a Primer Binding Site (PBS), two Open Reading Frames (ORFs) for ''gag'', and ''pol'' genes, and a Polypurine Tract (PPT) adjacent to the 3´LTR ([[Literature:85408|Nielsen, Hermansen and Aleksenko 2000]]). A chromodomain is detectable at the C-terminal end of the integrase domain of this element. The PBS of fungi and vertebrate chromoviruses, differs significantly from that used by plant chromoviruses. While plant chromoviruses use a methionine starting tRNA (iMet), fungi and vertebrate chromoviruses use their own self-priming mechanism to start the reverse transcription ([[Literature:43217|Levin 1995 ]]; [[Literature:10125|Butler et al. 2001]]).
|structure=Dane-1.png
|host=Aspergillus nidulans
|hostpic=Aspergillus_nidulans.gif
|literature=*[[Literature:15303|Mobile DNA II. (Craig et al. 2002)]]
|picowner=[http://www3.gettysburg.edu/~rcavalie/ralph.html Image, courtesy of Ralph Cavaliere, Gettysburg College]
}}

Element:Dane-1 - Revision history

imported>Gydbwiki at 16:26, 11 November 2009