https://gydb.org/index.php?action=history&feed=atom&title=Element%3ADrFV-1 2026-06-09T18:15:21Z Revision history for this page on the wiki MediaWiki 1.35.0 https://gydb.org/index.php?title=Element:DrFV-1&diff=577&oldid=prev 2010-05-04T08:54:15Z

<p></p> <p><b>New page</b></p><div>{{Element<br /> |genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&amp;val=85857417 85857417]<br /> |type= <br /> Undetermined<br /> |genus=<br /> Spumaretrovirus<br /> |subfamily=<br /> Class 3<br /> |family=<br /> Retroviridae<br /> |group=<br /> LTR retroelements<br /> |description=<br /> ''Danio rerio Foamy Virus type 1'' (DrFV-1) is a foamy retrovirus originally characterized in the genome of the ''Danio rerio'' zebrafish ([[Literature:100596|Llorens ''et al.'' 2009]]). This element belongs to the genus ''Spumaretrovirus'' (for a review see [[Literature:49494|Meiering and Linial 2001]]). The presence of this element in ''Danio rerio'' suggests that spumaretroviruses are more widely distributed than previously thought, as the remaining spumaretroviruses known so far are restricted to synapsids (mammals and their extincted relatives) (for more information about spumaretroviruses, see [[Literature:100615| Katzourakis ''et al.'' 2009]]). Further analyses are anyway required to clarify whether spumaretroviruses also inhabit (or circulate in) the genomes of other fishes, amphibians and sauropsids, in order to calibrate the origin of spumaretroviruses.<br /> <br /> The genomic structure of DrFV-1 is 12 Kb in size including LTRs of approximately 0.8 Kb. The internal region of this retrovirus displays a Primer Binding Site (PBS), Open Reading Frames (ORFs) for the typical ''gag'' and ''pol'' genes of retroviruses and LTR retrotransposons plus four additional ORFs that show no similarity to any sequence currently known (including ''env'') ([[Literature:100596|Llorens ''et al.'' 2009]]). It is thus unclear if DrFV-1 is a true retrovirus carrying a highly divergent ''env'' plus two accessory or additional genes or a LTR retrotransposon just carrying three additional genes. This suggests that DrFV-1 might be an intermediate sequence between ''Retroviridae'' retroviruses and other related LTR retrotransposons ([[Literature:100596|Llorens ''et al.'' 2009]]) <br /> |structure=DrFV-1.png<br /> |host= Danio rerio<br /> |hostpic=<br /> Danio_rerio.jpg<br /> |literature=*[[Literature:14014|Retroviruses. (Coffin, Hugges and Varmus 1997)]]<br /> |picowner=[http://es.wikipedia.org/wiki/Archivo:Zebrafisch.jpg Image, courtesy of Wikipedia]<br /> }}<br /> [[Category:Element]]</div>

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