imported>Gydbwiki at 08:33, 4 May 2010

2010-05-04T08:33:33Z

New page

{{Element
|genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=332610 M26927]
|type=
Undetermined
|genus=
Gammaretrovirus
|subfamily=
Class 1
|family=
Retroviridae
|group=
LTR retroelements
|description=''Gibbon Ape Leukemia Virus'' (GaLV) is a C-type oncogenic virus that induces myeloid leukemia in young gibbons. GaLV infects an especially large variety of cellular types in various species ([[Literature:85410|Johann, Gibbons and O’Hara 1992]]; [[Literature:85486|Hunter 1997]]). This evidence has been useful in developing genetic transference viral vectors ''in vivo'' and ''ex vivo'' ([[Literature:85411|Miller ''et al.'' 1991]]; [[Literature:82980|Wilson ''et al.'' 1989]]). The genomic structure of GaLV is 8.1 Kb size including pro-5´LTR and pro-3´LTR of 125 and 437 nt, respectively. The internal region of this retrovirus displays a Primer Binding Site (PBS) complementary to a tRNA<sup>Pro</sup>, Open Reading Frames (ORFs) for ''gag-pol'' and ''env'' genes characteristic of retroviruses, and a Polypurine Tract (PPT) adjacent to the 3´LTR ([[Literature:85393|Delassus, Sonigo and Wain-Hobson 1989]]).
|structure=Galv.png
|host=Hylobates syndactylus
|hostpic=Hylobates_syndactylus.gif
|literature=
*[[Literature:14014|Retroviruses. (Coffin, Hugges and Varmus 1997)]]
|picowner=[http://www.primates.com/welcome.htm Image, courtesy of David Pearce, primates.com]
}}

Element:GaLV - Revision history

imported>Gydbwiki at 08:33, 4 May 2010