imported>Gydbwiki at 08:34, 4 May 2010

2010-05-04T08:34:40Z

New page

{{Element
|genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=3309122 AF053745]
|type=
Undetermined
|genus=
Gammaretrovirus
|subfamily=
Class 1
|family=
Retroviridae
|group=
LTR retroelements
|description=''Mus dunni Endogenous Retrovirus'' (MdEV) is a murine retrovirus originally isolated in ''Mus dunni'' wild mouse during experiments with human cells in order to obtain competent virus replicates in human transference experiments ([[Literature:50316|Miller ''et al.'' 1996]]). MdEV is activated in response to 5-iode-2*deoxiuridine or hydrocortisone treatment. Various interference analyses have reported that MdEV, as opposed to other murine retroviruses, uses six different receptors to penetrate its host ([[Literature:50315|Miller and Wolgamot 1997]]; [[Literature:7665|Bonham, Wolgamot, and Miller 1997]]). The genomic structure of MdEV is 8.6 Kb in size including pro-LTRs 5′ and 3′ of 179 and 770 nt respectively. The internal region displays a Primer Binding Site (PBS) complementary to a tRNA<sup>Gly</sup>, Open Reading Frames (ORFs) for ''gag-pol'' and ''env'' genes characteristic of retroviruses, and a Polypurine Tract (PPT) adjacent to the 3´LTR ([[Literature:83382|Wolgamot, Bonham and Miller 1998]]).
|structure=Mdev.png
|host=Mus sp.
|hostpic=Mus_sp.gif
|literature=
*[[Literature:14014|Retroviruses. (Coffin, Hugges and Varmus 1997)]]
|picowner=[http://www.biotechvana.com Image, Joaquin Panadero, <br>Copyright, GyDB, Biotech Vana]
}}

Element:MdEV - Revision history

imported>Gydbwiki at 08:34, 4 May 2010