https://gydb.org/index.php?action=history&feed=atom&title=Element%3APERV-MSL 2026-06-09T16:10:15Z Revision history for this page on the wiki MediaWiki 1.35.0 https://gydb.org/index.php?title=Element:PERV-MSL&diff=398&oldid=prev 2010-05-04T08:36:07Z

<p></p> <p><b>New page</b></p><div>{{Element<br /> |genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&amp;val=3133301 AF038600]<br /> |type= <br /> Undetermined<br /> |genus=<br /> Gammaretrovirus<br /> |subfamily=<br /> Class 1<br /> |family=<br /> Retroviridae<br /> |group=<br /> LTR retroelements<br /> |description=''Porcine Endogenous Retrovirus'' (PERV-MSL) is a simple retrovirus isolated from lymphocytes of miniature swine. Constitutive production of PERV-MSL RNAs has been detected in normal leukocytes and in multiple organs of swine. The copy numbers of full-length PERV sequences per genome (approximately 8 to 15) vary among swine strains ([[Literature:814|Akiyoshi ''et al.'' 1998]]). Phylogenetically, PERV-MSL belongs to the genus ''Gammaretrovirus'' and is morphologically consistent with mammalian C-type retroviruses. The genomic structure of PERV-MSL is 8.13 Kb size including LTRs of 564 and 458 nt. The internal region of this retrovirus displays a Primer Binding Site (PBS) complementary to a tRNA&lt;sup&gt;Pro&lt;/sup&gt;, Open Reading Frames (ORFs) for the ''gag'', ''pol'' and ''env'' genes characteristic of retroviruses, and a Polypurine Tract (PPT) adjacent to the 3&amp;acute;LTR ([[Literature:814|Akiyoshi ''et al.'' 1998]]).<br /> |structure=Perv-msl.png<br /> |host=Sus scrofa<br /> |hostpic=Sus_scrofa.gif<br /> |literature=<br /> *[[Literature:14014|Retroviruses. (Coffin, Hugges and Varmus 1997)]]<br /> |picowner=[http://www.hiv-monitoring.nl/index.jsp?USMID=18 Image, Daniela Bezemer, HIV monitoring]<br /> }}</div>

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