https://gydb.org/index.php?action=history&feed=atom&title=Element%3APyERV 2026-06-09T14:56:29Z Revision history for this page on the wiki MediaWiki 1.35.0 https://gydb.org/index.php?title=Element:PyERV&diff=579&oldid=prev 2010-05-03T07:57:43Z

<p></p> <p><b>New page</b></p><div>{{Element<br /> |genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&amp;val=26006403 26006403]<br /> |type= Undetermined<br /> |genus=Betaretrovirus<br /> |subfamily= Class 2<br /> |family= Retroviridae<br /> |group= LTR retroelements<br /> |description= ''Python endogenous retrovirus'' (PyERV) is a retrovirus originally isolated from ''Python'' species ([[Literature:32642|Huder ''et al.'' 2002]]). PyERV belongs to genus ''Betaretrovirus'' within ''Retroviridae'' family (''International Committee on the Taxonomy of Viruses'' -ICTV- [[Literature:100589|Fauquet ''et al''. 2005]]) and according to [[Literature:100596|Llorens ''et al''. 2009]] is located within Class 2 of the [[Retroviridae|''Retroviridae'']] family. <br /> <br /> The genomic structure of PyERV is 7.0 Kb in size, including LTRs of 330 pb approximately ([[Literature:32642|Huder ''et al.'' 2002]]). The internal region of this element displays a Primer Binding Site (PBS) complementary to a tRNA&lt;sup&gt;Trp&lt;/sup&gt;, two Open Reading Frames (ORFs) coding for two gag-pol and env polyproteins (gag-pol includes the dUTPase-protease characteristic of betaretroviruses) and a Polypurine Tract (PPT) adjacent to the 3&amp;acute;LTR ([[Literature:32642|Huder ''et al.'' 2002]]). PyERV also shows an additional ORF ([[Literature:32642|Huder ''et al.'' 2002]]) overlaping gag-pol, which was later identified as the typical ORFX of betaretroviruses ([[Literature:93206|Llorens ''et al.'' 2008]]). For simplicity´s sake, the figure below shows an idealized single genomic organization) as the internal coding region of PyERV is disrupted by several stop codons and frameshiftings (see also, [[Literature:32642|Huder ''et al.'' 2002]]). <br /> |structure=PyERV.png<br /> |host=Phyton molurus<br /> |hostpic=Phyton.jpg<br /> |literature=*[[Literature:14014|Retroviruses. (Coffin, Hugges and Varmus 1997)]]<br /> |picowner=[http://www.biotechvana.com Image, Laura Covelli, &lt;br&gt;Copyright, GyDB, Biotech Vana]<br /> }}<br /> [[Category:Element]]</div>

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