https://gydb.org/index.php?action=history&feed=atom&title=Element%3ATF1 2026-06-09T19:34:15Z Revision history for this page on the wiki MediaWiki 1.35.0 https://gydb.org/index.php?title=Element:TF1&diff=426&oldid=prev 2009-11-11T16:39:53Z

<p></p> <p><b>New page</b></p><div>{{Element<br /> |genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&amp;val=173476 M38526]<br /> |type= <br /> TF1-2<br /> |genus=<br /> Fungi and vertebrates<br /> |subfamily=<br /> Chromoviruses<br /> |family=<br /> Ty3/Gypsy<br /> |group=<br /> LTR retroelements<br /> |description=TF1 is an active LTR retrotransposon characterized, along with TF2, in ''Schizosaccharomyces pombe'' ([[Literature:85443|Levin, Weaver and Boeke 1990]]; [[Literature:81840|Weaber et al. 1993]]). TF1 and TF2 are related to the ''Chromoviridae'' branch, term suggested ([[Literature:47259|Mar&amp;iacute;n and Llor&amp;eacute;ns 2000]]) to describe the ''Ty3/Gypsy'' elements bearing chromodomain-integrases ([[Literature:46552|Malik and Eickbush 1999]]). The chromovirus branch is probably the most ancient phylogenetic pattern of ''Ty3/Gypsy'' retroelements ([[Literature:26737|Gorinsek, Gubensek and Kordis 2004]]; [[Literature:26736| 2005]]; [[Literature:39523|Kordis 2005]]).<br /> <br /> The genomic structure of TF1 is 4.9 Kb in size, including LTRs of 358 nt. The internal region displays a Primer Binding Site (PBS), a single Open Reading Frame (ORF) ''gag-pol'', and a Polypurine Tract (PPT) adjacent to the 3&amp;acute;LTR ([[Literature:85443|Levin, Weaver and Boeke 1990]]; [[Literature:81840|Weaber et al. 1993]]). Neither, TF1 nor TF2 codify for chromodomain-containing integrases. The PBS of fungi and vertebrate chromoviruses, differs significantly from that used by plant chromoviruses. While plant chromoviruses use a methionine starting tRNA (iMet), fungi and vertebrate chromoviruses use their own self-priming mechanism to start the reverse transcription ([[Literature:43217|Levin 1995 ]]; [[Literature:10125|Butler et al. 2001]]).<br /> |structure=Tf1.png<br /> |host=Schizosaccharomyces pombe<br /> |hostpic=Schizosaccharomyces_pombe.gif<br /> |literature=*[[Literature:15303|Mobile DNA II. (Craig et al. 2002)]]<br /> |picowner=[http://bernhardt.biochem.uni-sb.de/ Image, courtesy of Rita Bernhardt, Lehrstuhl fur Biochemie, Universitat des Saarlandes]<br /> }}</div>

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