imported>Lcovelli at 14:58, 24 May 2010

2010-05-24T14:58:51Z

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{{Element
|genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=453579 453579]
|type= Tas
|genus= Undetermined
|subfamily= Branch 1
|family= Bel/Pao
|group= LTR retroelements
|description= ''Tas'' is a potential retrovirus described in the genome of the "giant intestinal roundworm" ''Ascaris lumbricoides'' ([[Literature:100599|Aeby'' et al.'' 1986]]). ''Tas'' is the first retrovirus-like element found in any nematode species and received its name standing for transposon-like element of ''Ascaris'' ([[Literature:100599|Aeby'' et al.'' 1986]]). Two variant forms present in the germ line - Tas-1 (the most abundant) and Tas-2 - have been characterized and approximately 50 copies are dispersed over about of 20 different chromosomal sites ([[Literature:100599|Aeby'' et al.'' 1986]]). ''Tas'' gives the name and belongs to ''Tas'' clade ([[Literature:14755|Copeland ''et al.'' 2005]]) within Branch 1 of the ''Bel/Pao'' family ([[Literature:100596|Llorens ''et al.'' 2009]]).
The genome of ''Tas'' is 7.6 Kb in size (7627 bp in length), including LTRs of respectively 256 (5’LTR) and 250 nts (3’LTR). The internal region of this element contains a Primer Binding Site (PBS), complementary to a tRNA<sup>Arg</sup>, a coding region and a Polypurine Tract (PPT) upstream of the 3´LTR ([[Literature:100599|Aeby'' et al.'' 1986]]; [[Literature:21668|Felder ''et al.'' 1994]]). Although the coding region is disrupted by several stop codons and frameshiftings, the distinct ''gag'' and ''pol'' domains typical of LTR retrotransposons are clearly evident. In the ''Tas'' genome has also been identified an ''env''-like gene located adjacent to the 3' LTR ([[Literature:21668|Felder ''et al.'' 1994]]).
|structure=tas.png
|host=Ascaris lumbricoides
|hostpic=Ascaris_lumbricoides.png
|literature=*[[Literature:15303|Mobile DNA II. (Craig et al. 2002)]]
|picowner=[http://www.dpd.cdc.gov/dpdx/HTML/Image_Library.htm Cortesy of CDC-DPDx]
}}
[[Category:Element]]

Element:Tas - Revision history

imported>Lcovelli at 14:58, 24 May 2010