https://gydb.org/index.php?action=history&feed=atom&title=Element%3ATy2 2026-06-09T19:34:42Z Revision history for this page on the wiki MediaWiki 1.35.0 https://gydb.org/index.php?title=Element:Ty2&diff=599&oldid=prev 2010-01-27T16:38:48Z

<p></p> <p><b>New page</b></p><div>{{Element<br /> |genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&amp;val=632669 632669 (nts 4392-10350)]<br /> |type= Ty (Pseudovirus)<br /> |genus=Pseudovirus<br /> |subfamily=Branch 1<br /> |family= Ty1/Copia<br /> |group= LTR retroelements<br /> |description=''Ty2'' is representative of one of the four LTR retrotransposon sets (''Ty1'','' Ty2'', ''Ty3'' and ''Ty4'') described in the genome of yeast ''Saccharomyces cerevisiae'' ([[Literature:100661|Boeke and Sandmeyer 1991]]). ''Ty2'' belongs to ''Ty (Pseudovirus)'' clade one of the three original genera on which the in-progrees ''Pseudoviridae'' classification is constituted ([[Literature:100591|Boeke ''et al'' 2005]]).<br /> <br /> The genome of ''Ty2'' is 5959 bp in size, including two 332-bp LTRs that flank an internal region bounded upstream and downstream by a Primer Binding Site (PBS), complementary to a tRNA&lt;sup&gt;iMet&lt;/sup&gt;, and a Polypurine Tract (PPT1), respectively. Interestingly, a second sequence very similar to the PPT1 was found near the middle of the ''pol'' gene (PTT2). The coding internal region displays two overlapping Open Reading Frames (ORFs): the first contains the gag protein while the second the typical ''Ty1/Copia'' pol-polyprotein domains (protease, integrase, reverse transcriptase and ribonuclease H) ([[Literature:100661|Boeke and Sandmeyer 1991]]). The gag-associated RNA-binding motif (CCHC) has not been identified in this element ([[Literature:59075|Peterson-Burch and Voytas 2002]]). The central PPT2 has been demonstrated to be not essential for the element transposition ([[Literature:30799|Heyman ''et al.'' 2003]]; [[Literature:23281|Friant ''et al.'' 1996]]). <br /> |structure=Ty2.png<br /> |host=Saccharomyces cerevisiae<br /> |hostpic=Saccharomyces_cerevisiae.gif<br /> |literature=*[[Literature:15303|Mobile DNA II. (Craig ''et al.'' 2002)]]<br /> |picowner=[http://www.biotechvana.com Image, Joaquin Panadero, &lt;br&gt;Copyright, GyDB, Biotech Vana]<br /> }}<br /> [[Category:Element]]</div>

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