https://gydb.org/index.php?action=history&feed=atom&title=Element%3ATy4 2026-06-09T17:28:52Z Revision history for this page on the wiki MediaWiki 1.35.0 https://gydb.org/index.php?title=Element:Ty4&diff=598&oldid=prev 2010-01-27T16:35:41Z

<p></p> <p><b>New page</b></p><div>{{Element<br /> |genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&amp;val=1218005 1218005 (nts 153-6362)]<br /> |type= Ty (Pseudovirus)<br /> |genus=Pseudovirus<br /> |subfamily=Branch 1<br /> |family= Ty1/Copia<br /> |group= LTR retroelements<br /> |description=''Ty4'' is representative of one of the four LTR retrotransposon sets (''Ty1'','' Ty2'', ''Ty3'' and ''Ty4'') described in the genome of yeast ''Saccharomyces cerevisiae'' ([[Literature:100661|Boeke and Sandmeyer 1991]]; [[Literature:34419|Janetzky and Lehle 1992]]). It shows the greatest similarity with ''Ty2'' and ''Ty1'' elements and with them represents one of the members of ''Ty (Pseudovirus)'' clade, one of the three original genera on which the in-progrees ''Pseudoviridae'' classification is constituted ([[Literature:100591|Boeke ''et al'' 2005]]).<br /> <br /> ''Ty4'' genome is about of 6.2 Kb in size, including two 371-bp LTRs ([[Literature:72924|Stucka ''et al.'' 1992]]; [[Literature:34419|Janetzky and Lehle 1992]]). The LTRs flanked internal region contains two overlapping open reading frames (ORFs): the first ORF, TYA4, encodes a protein with the conserved motif (CCHC) found in the nucleic acid-binding gag-protein of retroviruses; the second ORF, TYB4, encodes a polyprotein showing domains with significant homology to the ''Ty1/Copia''-like protease, integrase, reverse transcriptase, and RNase H (structurally arranged in this order) ([[Literature:34419|Janetzky and Lehle 1992]]; [[Literature:72924|Stucka ''et al.'' 1992]]). A potential primer binding site is located downstream to the 5’LTR, it differs from those of the other yeast Ty elements to be complementary to a tRNA&lt;sup&gt;Asn&lt;/sup&gt; ([[Literature:54327|Neuvéglise ''et al.'' 2002]]).<br /> |structure=Ty4.png<br /> |host=Saccharomyces cerevisiae<br /> |hostpic=Saccharomyces_cerevisiae.gif<br /> |literature=*[[Literature:15303|Mobile DNA II. (Craig ''et al.'' 2002)]]<br /> |picowner=[http://www.biotechvana.com Image, Joaquin Panadero, &lt;br&gt;Copyright, GyDB, Biotech Vana]<br /> }}<br /> [[Category:Element]]</div>

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