imported>Gydbwiki at 08:08, 4 May 2010

2010-05-04T08:08:34Z

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{{Element
|genbank=[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=2801519 AF033822]
|type=
Undetermined
|genus=
Epsilonretrovirus
|subfamily=
Class 1
|family=
Retroviridae
|group=
LTR retroelements
|description=''Walleye Dermal Sarcoma Virus'' (WDSV) is a complex fish retrovirus characterized in ''Stizostedion vitreum'' (walleye). WDSV is responsible for a skin tumour called walleye dermal sarcoma that produces seasonal lesions that appear in the winter and disappear in the summer ([[Literature:85421|Bowser ''et al.'' 1988]]; [[Literature:85422|Martineau ''et al.'' 1990]]; [[Literature:85423|Martineau ''et al.'' 1992]]). Phylogenetically, WDSV is close to gammaretroviruses which usually are simple retroviruses. However, WDSV has several accessory genes and is therefore, a complex retrovirus constituting an own genus. The genomic structure of WDSV genome is 12.7 Kb size including pro-LTRs of 151 nt and 1.034 nt, respectively. The internal region of this retrovirus displays a Primer Binding Site (PBS) complementary to a tRNA<sup>His</sup>, Open Reading Frames (ORFs) for ''gag-pol'', and ''env'' genes characteristic of retroviruses, three accessory genes named ''OrfA'' (cicline-related), ''OrfB'', and ''OrfC'', this latter located between the U5 and ''gag'' gene, and also, a Polypurine Tract (PPT) adjacent to the 3´ LTR ([[Literature:31845|Holzschu ''et al.'' 1995]]; [[Literature:41704|Lapierre, Casey and Holzschu 1998]] , [[Literature:14014|Coffin, Hugges and Varmus, Map 13 1997]]).
|structure=Wdsv.png
|host=Stizostedion vitreum
|hostpic=Stizostedion_vitreum.gif
|literature=
*[[Literature:14014|Retroviruses. (Coffin, Hugges and Varmus 1997)]]
|picowner=[http://www.aquariacentral.com Image, Courtesy of Aquaria Central]
}}

Element:WdSV - Revision history

imported>Gydbwiki at 08:08, 4 May 2010