https://gydb.org/index.php?action=history&feed=atom&title=KRAB 2026-06-09T20:12:08Z Revision history for this page on the wiki MediaWiki 1.35.0 https://gydb.org/index.php?title=KRAB&diff=1303&oldid=prev 2011-11-07T10:44:24Z

<p></p> <p><b>New page</b></p><div>[http://supfam.cs.bris.ac.uk/SUPERFAMILY/cgi-bin/scop.cgi?sunid=109640 ''KRAB''] (Krüppel-associated box) domain is a transcription repression module found in a subfamily of C2H2 zinc finger proteins ([[literature:100816|Bellefroid ''et al''. 1999]]) and generally encoded by two exons, ''KRAB-A'' involved in repression and ''KRAB-B'' thought to act as enhancer for the A box repression. Whether or not the domain contains the A box, the B box, or both, it is always known as the ''KRAB'' domain ([[literature:100846|Urrutia 2006]]). <br /> <br /> ''KRAB-A'' domain is present at N-terminus in ''KRBA2'' variants of [[SCAN/KRAB|''SCAN/KRAB'']] cellular integrases. The presence of ''KRAB-A'' box in ''KRBA2'' proteins with no additional zinc finger domain more than that of [[Integrase|Integrase]] is strikingly particular and up to our knowledge no details on potential function has been reported.</div>

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